Efficient channel equalization algorithms for multicarrier communication systems

Blind adaptive algorithm that updates time-domain equalizer (TEQ) coefficients by Adjacent Lag Auto-correlation Minimization (ALAM) is proposed to shorten the channel for multicarrier modulation (MCM) systems. ALAM is an addition to the family of several existing correlation based algorithms that can achieve similar or better performance to existing algorithms with lower complexity. This is achieved by designing a cost function without the sum-square and utilizing symmetrical-TEQ property to reduce the complexity of adaptation of TEQ to half of the existing one. Furthermore, to avoid the limitations of lower unstable bit rate and high complexity, an adaptive TEQ using equal-taps constraints (ETC) is introduced to maximize the bit rate with the lowest complexity. An IP core is developed for the low-complexity ALAM (LALAM) algorithm to be implemented on an FPGA. This implementation is extended to include the implementation of the moving average (MA) estimate for the ALAM algorithm referred as ALAM-MA. Unit-tap constraint (UTC) is used instead of unit-norm constraint (UNC) while updating the adaptive algorithm to avoid all zero solution for the TEQ taps. The IP core is implemented on Xilinx Vertix II Pro XC2VP7-FF672-5 for ADSL receivers and the gate level simulation guaranteed successful operation at a maximum frequency of 27 MHz and 38 MHz for ALAM-MA and LALAM algorithm, respectively. FEQ equalizer is used, after channel shortening using TEQ, to recover distorted QAM signals due to channel effects. A new analytical learning based framework is proposed to jointly solve equalization and symbol detection problems in orthogonal frequency division multiplexing (OFDM) systems with QAM signals. The framework utilizes extreme learning machine (ELM) to achieve fast training, high performance, and low error rates. The proposed framework performs in real-domain by transforming a complex signal into a single 2–tuple real-valued vector. Such transformation offers equalization in real domain with minimum computational load and high accuracy. Simulation results show that the proposed framework outperforms other learning based equalizers in terms of symbol error rates and training speeds

Precoding in MIMO, OFDM to reduce PAPR (Peak to Average Power Ratio)

One of the critical issues of systems utilizing Orthogonal Frequency Division Multiplexing (OFDM) is the high peak to the average power ratio of OFDM signals. We have used Precoding as a way to mitigate the PAPR problem. Furthermore the performance of Precoded OFDM in fading multi-path channels has been studied. This thesis is based on an efficient technique for reducing the PAPR of OFDM signals. The proposed technique is data-independent and thus, does not require new processing and optimization for each transmitted OFDM block. The reduction in PAPR of the OFDM signal is obtained through a proper selection of a Precoding scheme that distributes the power of each modulated symbol over the OFDM block. The obtained results show that this Precoding scheme is an attractive solution to the PAPR problem of OFDM signals

Challenges in conducting online assessments in undergraduate medical and dental education: a scoping review

Online assessment in medical education is relatively new and there is a paucity of literature available on this topic. The objective of this scoping review was to conduct a systematic search of the published literature on the challenges of conducting online assessments in undergraduate medical and dental curricula. The literature was searched in the recommended electronic databases. The search terms used were &ldquo;online assessments, e-assessments, computer-assisted assessments, online assessment challenges and opportunities, online assessments in medical education, reliability and validity of online assessments, and online assessments during COVID-19 pandemic&rdquo; in PubMed Central, Google Scholar, Wiley Online Library, SpringerLink, and Ovid. After screening, 21 full-text articles were included in this scoping review. The data were charted independently and synthesized to present the findings.Most of the studies included in this review were published in the year 2020 and 2021(till September). Half of the studies (50%) reported that cheating and plagiarism are the most common challenges in online assessments, while a similar number of studies highlighted the issues faced by the teachers in making and conducting online assessments. Similarly, 22% of the studies emphasized the concerns raised by the students, while another 22% reported the technical and financial issues faced by the institutions in conducting online assessments. It was revealed that during COVID-19 the biggest challenge for the educational system was to switch to online assessments, as the educational system was not ready for it. Few studies (16%) reported that the issues of reliability and validity of online assessments are still to uncover. This scoping review may help to lay the foundation for more empirical future studies on the challenges of conducting online assessments in the undergraduate medical and dental curricula in Pakistan.</p

<i>Monotheca buxifolia</i> Driven Synthesis of Zinc Oxide Nano Material Its Characterization and Biomedical Applications

The current study demonstrates a sophisticated and environmentally friendly synthesis of zinc oxide nanoparticles (ZnO-NPs) for a range of biological and environmental applications using Monotheca buxifolia as a bio-source. At the nanometer scale, a simple aqueous extract from Monotheca buxifolia was used to convert Zn into stable elemental zinc (Zn0). With an average size of 45.8 nm and a spherical shape, the NPs were stable and pure. The nanoparticles studied here were tested in vitro for bactericide, fungicide, biocompatibility, leishmaniasis, anti-diabetic effect, antioxidant effect, and anti-Alzheimer’s effect. According to our results, Monotheca buxifolia mediated ZnO-NPs are highly effective against spore-forming fungal strains and MDR bacterial strains. All examined bacterial isolates of UTI (urinary tract infection) were resistant to non-coated antibiotics; however, adding 1% of the produced ZnO-NPs to the treatments increased their bactericidal activity significantly. The NPs also showed dose-dependent cytotoxicity against Leishmania tropica parasites, with an LC50 of 248 μg/mL for promastigote parasites and 251 μg/mL for amastigote parasites. In addition, a significant inhibition of α-glucosidase, α-amylase, butyrylcholinesterase (BChE), and acetylcholinesterase (AChE) was discovered, indicating anti-Alzheimer’s and anti-diabetic effects. The biocompatibility of the particles with human red blood cells was also observed. Due to their environmentally friendly production, biological safety, and exceptional physicochemical properties, ZnO-NPs could be used as a new competitor for several biological and environmental applications

Multi-element uptake and growth responses of Rice (Oryza sativa L.) to TiO2 nanoparticles applied in different textured soils

The aim of present work was to evaluate the effects of titanium dioxide nanoparticles (TiO2 NPs) on rice’s growth (Oryza sativa L.) and nutrient availability under different soil textures. Greenhouse experiment was carried out with three soil textures (sandy loam, silt loam and silty clay loam) and two concentrations of TiO2 NPs (500, 750 mg kg−1). Control (without TiO2 NPs) was also maintained for the comparison. Growth parameters including chlorophyll content, root/shoot length, fresh/dry biomass and nutrients’ uptake including calcium (Ca), copper (Cu), iron (Fe), magnesium (Mg), phosphorous (P), potassium (K) and zinc (Zn) were determined. The results revealed that application of 500 mg kg−1 TiO2 NPs in silty clay loam soil increased the chlorophyll content (3.3-folds), root length (49%), shoot length (31%), root and shoot biomass (41% &amp; 39%, respectively) as compared to other soil textures. The maximum plant growth was observed in silty clay loam > silt loam > sandy loam. Concentration of Cu, Fe, P and Zn in shoot was increased by 8 − , 2.3 − , 0.4 − , 0.05 −folds in silty clay loam upon 500 mg kg−1 TiO2 NPs application as compared to the control. Backward selection method to model the parameters (nutrients in soil) for the response variables (root/shoot length and biomass) showed that Ca, Fe, P are the main nutrients responsible for the increase in plant length and biomass. Overall, the growth of rice was better in silty clay loam at 500 mg kg−1 of TiO2 NPs

Association of the 9p21.3 locus with risk of first-ever myocardial infarction in Pakistanis: Case-control study in South Asia and updated meta-analysis of Europeans

Objective: To examine variants at the 9p21 locus in a case-control study of acute myocardial infarction (MI) in Pakistanis and to perform an updated meta-analysis of published studies in people of European ancestry.Methods and results: A total of 1851 patients with first-ever confirmed MI and 1903 controls were genotyped for 89 tagging single-nucleotide polymorphisms at locus 9p21, including the lead variant (rs1333049) identified by the Wellcome Trust Case Control Consortium. Minor allele frequencies and extent of linkage disequilibrium observed in Pakistanis were broadly similar to those seen in Europeans. In the Pakistani study, 6 variants were associated with MI (P\u3c10(-2)) in the initial sample set, and in an additional 741 cases and 674 controls in whom further genotyping was performed for these variants. For Pakistanis, the odds ratio for MI was 1.13 (95% CI, 1.05 to 1.22; P=2 x 10(-3)) for each copy of the C allele at rs1333049. In comparison, a meta-analysis of studies in Europeans yielded an odds ratio of 1.31 (95% CI, 1.26 to 1.37) for the same variant (P=1 x 10(-3) for heterogeneity). Meta-analyses of 23 variants, in up to 38,250 cases and 84,820 controls generally yielded higher values in Europeans than in Pakistanis.Conclusions: To our knowledge, this study provides the first demonstration that variants at the 9p21 locus are significantly associated with MI risk in Pakistanis. However, association signals at this locus were weaker in Pakistanis than those in European studies

Genetic determinants of major blood lipids in Pakistanis compared with Europeans.

BACKGROUND: Evidence is sparse about the genetic determinants of major lipids in Pakistanis. METHODS AND RESULTS: Variants (n=45 000) across 2000 genes were assessed in 3200 Pakistanis and compared with 2450 Germans using the same gene array and similar lipid assays. We also did a meta-analysis of selected lipid-related variants in Europeans. Pakistani genetic architecture was distinct from that of several ethnic groups represented in international reference samples. Forty-one variants at 14 loci were significantly associated with levels of HDL-C, triglyceride, or LDL-C. The most significant lipid-related variants identified among Pakistanis corresponded to genes previously shown to be relevant to Europeans, such as CETP associated with HDL-C levels (rs711752; P<10(-13)), APOA5/ZNF259 (rs651821; P<10(-13)) and GCKR (rs1260326; P<10(-13)) with triglyceride levels; and CELSR2 variants with LDL-C levels (rs646776; P<10(-9)). For Pakistanis, these 41 variants explained 6.2%, 7.1%, and 0.9% of the variation in HDL-C, triglyceride, and LDL-C, respectively. Compared with Europeans, the allele frequency of rs662799 in APOA5 among Pakistanis was higher and its impact on triglyceride concentration was greater (P-value for difference <10(-4)). CONCLUSIONS: Several lipid-related genetic variants are common to Pakistanis and Europeans, though they explain only a modest proportion of population variation in lipid concentration. Allelic frequencies and effect sizes of lipid-related variants can differ between Pakistanis and Europeans